PReS-FINAL-2320: Different clinical presentation of takayasu arthritis: case report of two pediatric patients

Introduction Takayasu arteritis (TA) is a granulomatous large vessel vasculitis that involves the aorta, its major branches and pulmonary arteries. Diagnosis of TA during childhood remains challenging due to the non-specific symptoms. It primarily affects East Asian women in their second or third decade of life but is well known to affect all ethnicities across the world. Given its systemic nature, Takayasu’s arteritis has multiorgan involvement, with the majority of disease morbidity related to the cardiovascular, central nervous, and renal systems. Despite the increasing identification of children and adolescents with TA, reports of disease in childrens population are still scarce.